Research in NeuroICU

NeuroICU at St. George’s University Hospitals NHS Foundation Trust is research active.

Research Team

NeuroICU and Neurosurgery at SGH collaborate closely within the field of research

Neuro Intensive care is affiliated with the Neuroscience and Cell Biology Research Institute at City St. George’s University, University of London https://www.sgul.ac.uk/about/our-institutes/neuroscience-and-cell-biology-research-institute

Dr Andrew Hitchings – Reader in Clinical Pharmacology & Honorary Consultant in NeuroICU https://orcid.org/0000-0002-2802-1466
Dr Argyro Zoumprouli – Hayler Senior Lecturer in NeuroIntensive Care & Honorary Consultant in NeuroICU https://orcid.org/0000-0003-0890-690X
Dr Marios Papadopoulos – Professor of Neurosurgery- https://orcid.org/0000-0001-9174-4176
Dr Samira Saadoun – Senior Lecturer in Neuroscience- https://orcid.org/0000-0002-5480-5678
Dr Ximena Watson – Consultant in NeuroICU- PI for Bonanza trial
Dr Maresa Santi – Consultant in NeuroICU – PI for Shorter Trial
Vincent Ventura – NeuroICU research nurse
Elaine Luzano – NeuroICU research nurse

Current Randomised Controlled Trials

The Neuro-ICU at St. George’s contributes to the following trials. Some of these trials have started recruitment and others are currently being set-up.

BONANZA

Traumatic brain Injury https://www.anzics.com.au/current-active-endorsed-research/bonanza/ 

Brain tissue oxygen monitoring from injured brain

Lead site: Monash University, Melbourne

SOS

Traumatic brain Injury https://fundingawards.nihr.ac.uk/award/17/120/01 

Mannitol vs hypertonic saline for raised intracranial pressure

Lead site: University Hospitals Birmingham NHS Foundation Trust

SIGNET

Statins for improving organ outcome in transplantation. https://fundingawards.nihr.ac.uk/award/NIHR131124

ISCoPE

Traumatic spinal cord injury https://www.clinicaltrials.gov/ct2/show/NCT02721615?term=ISCOPE&cond=Spinal+Cord+Injuries&draw=2&rank=1 

Multi-modality monitoring from injury site

Lead site: St George’s, University of London

To investigate whether giving deceased organ donors a single dose of the drug Simvastatin, very inexpensive and safe, is beneficial for transplant
recipients.

Lead site: St George’s, University of London